In depth analysis and explanation of retrospective and prospective molecular biotechnology methods. Most often utilized physiological models employed in the laboratory. Up-to-date education regarding medical laboratory analysis and interpretation of patient results. Medical pathophysiology of disease broken down into its respective pathological state and normal physiological mode.

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DARA-T Workup

Daratumumab (Darzalex) is an IgG1k monoclonal antibody directed against CD38, which is over expressed on the plasma cells in patients with multiple myeloma. Daratumumab binds to CD38 and causes apoptosis through antibody-dependent cellular cytotoxicity or complement-dependent cytotoxicity. In 2015 the FDA approved daratumumab for the treatment of refractory multiple myeloma. Refractory meaning that patients have … Continue reading DARA-T Workup

The Precipitation Curve

This article will review basic immunology principles by defining key terms and explaining different techniques and phenomenons. Key Definitions Sensitization is the basic reaction of an antigen and an antibody binding. During an antigen:antibody reaction, the antigen or the antibody can be measured using a variety of methods. Each method has its advantages and disadvantages. … Continue reading The Precipitation Curve

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