Approximately every 42 seconds an American will suffer from a myocardial infarction. A MI occurs in a hypoxic state and sections of the heart are unable to get the oxygen it needs. According to the CDC about 610,000 die of heart disease in the United States every year, an occurrence of about 1 in every … Continue reading Cardiac Markers
Lactate dehydrogenase (LD, LDH) is an enzyme that is found in all cells in all tissues of the body. It catalyzes the reversible conversion of lactate to pyruvic acid in glycolysis and gluconeogenesis. It is released from various anatomical sites of the body in response to cellular injury and damage. It is used as a … Continue reading Lactate Dehydrogenase
The patient was diagnosed with subclinical DIC because complications from Acute Promyelocytic Leukemia (APL) The characteristic chromosomal translocation of Acute Promyelocytic Leukemia is the break and fusion of the PML gene located on chromosome 15 and the RARA gene located on chromosome 17. This results in a t(15;17) which is detectable in more than 90% … Continue reading Case Study Mini-Series; Diagnosis
The purpose of this mini-series is to get in the mind of a treating physician when a patient such as this presents to the clinic or the ED in this case. The first part of this series is the introduction of the case with case history and initial lab testing. Please don't hesitate to leave … Continue reading 37-year-old South American Male Case Study Mini-Series
A few articles ago immunotherapy was mentioned and introduced via the usage and progression in the research of CAR-T therapy and its use with ALL (B-cell) and lymphomas. Another branch of immunotherapy is quietly emerging, called immune checkpoint inhibitors. Specifically for the treatment of Glioblastoma, which is an aggressive form of brain cancer. Glioblastomas (GBM) … Continue reading Immune Checkpoint Inhibitors Advance Treatment of Glioblastomas.